Interferon Lambda-1 (IFNL1) Antibody (FITC)
169€ (20 µg)
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name
Interferon Lambda-1 (IFNL1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx336178
Description
IFNL1 Antibody (FITC) is a Rabbit Polyclonal against IFNL1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interferon Lambda-1 (IFNL1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IU54 |
| Gene ID | 282618 |
| Alias | IL29,IL-29,IFN-lambda-1,Cytokine Zcyto21 |
| Background | Antibody anti-IFNL1 |
| Status | RUO |
Descripción
Interferon Lambda 1 (IFNL1), also known as IL-29, is a member of the Type III interferon family, which includes IFNL1, IFNL2 (IL-28A), and IFNL3 (IL-28B), and more recently discovered IFNL4. These cytokines are involved in antiviral immunity and have significant overlap in function with Type I interferons (such as IFN-α and IFN-β), but with distinct cellular targeting. IFNL1 plays a key role in the innate immune response, especially in protecting epithelial barriers, such as those found in the lungs, intestines, and liver, from viral infections. Unlike Type I interferons, which have broad activity across multiple cell types, Type III interferons like IFNL1 act primarily on cells that express the interferon lambda receptor (IFNLR1), which is most commonly found on epithelial cells and some immune cells like dendritic cells. This targeted action is thought to provide a more localized antiviral defense while minimizing the systemic inflammatory responses often seen with Type I interferons.
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