Interferon-Induced Protein With Tetratricopeptide Repeats 1 (IFIT1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Interferon-Induced Protein With Tetratricopeptide Repeats 1 (IFIT1) Antibody is a Rabbit polyclonal antibody for the detection of Human Interferon-Induced Protein With Tetratricopeptide Repeats 1 (IFIT1).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interferon-Induced Protein With Tetratricopeptide Repeats 1 (IFIT1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P09914 |
| Gene ID | 3434 |
| NCBI Accession | NP_001257857.1 |
| Background | Antibody anti-IFIT1 |
| Status | RUO |
Descripción
Related Products
Human IFIT1 (Interferon-induced protein with tetRatricopeptide repeats 1) ELISA Kit
Ver Producto
IFIT1 antibody
Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
Ver Producto