Interferon Gamma (IFNG) Antibody (FITC)
364€ (100 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Interferon Gamma (IFNG) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139547
Tested Applications
FCM
Description
Interferon Gamma Antibody is a Mouse Monoclonal against Interferon Gamma.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interferon Gamma (IFNG) Immunogen: Interferon gamma derived from Human leukocytes. |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | FCM: 4 µl reagent / 100 µl of whole blood or 106 cells in a suspension. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 Kappa |
| Clone ID | M720 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P01579 |
| Gene ID | 3458 |
| NCBI Accession | NP_997468.1 |
| OMIM | 147570 |
| Alias | IFG,IFI,IMD69,IFN-gamma,Immune interferon |
| Background | Antibody anti-IFNG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interferon Gamma (IFNG) is a pivotal cytokine of the immune system, classified as a type II interferon, and is primarily produced by activated T lymphocytes, natural killer (NK) cells, and NKT cells. Unlike type I interferons, IFNG signals through a distinct receptor, the interferon gamma receptor (IFNGR), leading to the activation of the JAK-STAT pathway and the induction of a unique set of genes critical for immune defense. IFNG plays a central role in coordinating both innate and adaptive immune responses, including macrophage activation for enhanced phagocytosis and antigen processing, upregulation of MHC class I and II molecules to improve antigen presentation, and stimulation of cytotoxic T cells. It is also essential in granuloma formation to contain intracellular pathogens, such as Mycobacterium tuberculosis. Dysregulation of IFNG activity is implicated in various inflammatory and autoimmune conditions, as well as chronic infections. Its therapeutic potential in immunotherapy and as a biomarker in certain cancers and infectious diseases remains an active focus of study.
Productos relacionados
Interferon Gamma (IFNG) Antibody
IFNG Antibody is a Rabbit Polyclonal antibody against IFNG. This gene encodes a member of the type II interferon family.…
Ver producto
Interferon Gamma (IFNG) Antibody
Interferon gamma (IFN gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainl…
Ver producto
Interferon Gamma (IFNG) Antibody
Interferon Gamma (interferon, gamma) is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natur…
Ver producto