Intercellular Adhesion Molecule 2 / CD102 (ICAM2) Antibody
494€ (200 µg)
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935106861
info@markelab.com
name
Intercellular Adhesion Molecule 2 / CD102 (ICAM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx412785
tested applications
WB, IF/ICC, FCM, IP
Description
Intercellular Adhesion Molecule 2 (CD102) Antibody is a Mouse Monoclonal antibody against Intercellular Adhesion Molecule 2 (CD102).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Intercellular Adhesion Molecule 2 / CD102 (ICAM2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 200 µg |
| Form | Liquid |
| Tested Applications | WB, IF/ICC, FCM, IP |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13598 |
| Alias | Intercellular adhesion molecule 2,CD102,ICAM-2 |
| Background | Antibody anti-ICAM2 |
| Status | RUO |
| Note | Concentration: 1.0 mg/ml - |
Descripción
Intercellular adhesion molecule 2 (ICAM2) is a member of the immunoglobulin superfamily and plays an essential role in immune cell trafficking, endothelial integrity, and cell signaling. ICAM-2 is encoded by the ICAM2 gene and, along with other intercellular adhesion molecules, serves as a ligand for leukocyte integrins such as LFA-1 (lymphocyte function-associated antigen-1), facilitating the adhesion and transmigration of leukocytes across endothelial cells. It is broadly expressed on endothelial cells, leukocytes, and various other cell types. ICAM-2 is involved in vascular and immune system homeostasis, with roles extending to inflammation, cancer, and neurological functions. Unlike ICAM-1, which is inducible by inflammatory cytokines, ICAM-2 is constitutively expressed but has been found to increase in certain pathophysiological conditions, especially involving endothelial activation. The stable presence of ICAM-2 on endothelial cells makes it significant for lymphocyte recirculation and endothelial-leukocyte interactions, aiding immune surveillance and response to pathogens.
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