Intelectin 1 (ITLN1) Antibody (Biotin)

Este producto es parte de ITLN - Intelectin (Omentin)
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351€ (200 µl)

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935106861
info@markelab.com
name
Intelectin 1 (ITLN1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx272759
tested applications
WB, IHC, IF/ICC

Description

Intelectin 1 (ITLN1) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Intelectin 1 (ITLN1).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Intelectin 1 (ITLN1)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
200 µl
Size 2
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
HL1,LFR,HL-1,INTL,ITLN,hIntL,omentin
Background
Antibody anti-ITLN1
Status
RUO

Descripción

ITLN1 is a secreted glycoprotein mainly expressed in adipose tissue, the small intestine, and the mesothelial cells It is known for its role in immune defense by binding to pathogen-associated carbohydrate structures, such as galactofuranose residues on microbial surfaces ITLN1 also acts as an adipokine, influencing insulin sensitivity and glucose metabolism through its association with obesity and metabolic diseases Decreased ITLN1 levels are linked to insulin resistance, type 2 diabetes, and obesity, while elevated levels are observed under conditions like calorie restriction or weight loss ITLN1 exerts anti-inflammatory and anti-oxidative effects, improving metabolic function by reducing inflammatory cytokine production and enhancing insulin signaling in skeletal muscle It is also involved in tissue repair and epithelial protection through its interaction with epithelial cell surfaces Dysregulation of ITLN1 expression is associated with cardiovascular diseases and inflammatory disorders, making it a potential therapeutic target for obesity-related metabolic dysfunction

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