Integrin Alpha IIb / CD41 (ITGA2B) Antibody (Biotin)
Pida mas información
935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-ITGA2B
proveedor
Abbexareference
abx304252Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ITGA2B Antibody (Biotin) is a Rabbit Polyclonal against ITGA2B conjugated to Biotin.
Background
ITGA2B, also known as integrin alpha 2b or CD41, is a transmembrane glycoprotein that plays a central role in platelet adhesion and aggregation. It is primarily expressed on platelets and megakaryocytes. Together with integrin beta 3 (ITGB3), ITGA2B forms the αIIbβ3 integrin complex (also known as GPIIb/IIIa), which is the most abundant integrin on the surface of platelets and is crucial for blood clot formation (hemostasis). This receptor mediates platelet aggregation by binding to fibrinogen, von Willebrand factor (vWF), fibronectin, and other adhesive proteins during platelet activation. When platelets are stimulated, the αIIbβ3 complex undergoes a conformational change that allows it to bind its ligands and mediate platelet-platelet interactions.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Integrin Alpha IIb / CD41 (ITGA2B)
host
Rabbit
isotype
IgG
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
ITGA2B
dry ice
No
availability
Shipped within 5-10 working days.
alias
GT,GT1,GTA,CD41,GP2B,HPA3,CD41B,GPIIb,BDPLT2,BDPLT16,PPP1R93,Integrin alpha-Iib,GPalpha IIb (GPIIb),Platelet membrane glycoprotein IIb
uniprot id
NCBI accession
NP_000410.2, NM_000419.4
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