Integrin Alpha IIb / CD41 (ITGA2B) Antibody (Biotin)

Este producto es parte de ITGA2B - integrin subunit alpha 2b
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364€ (0.1 mg)

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935106861
info@markelab.com
name
Integrin Alpha IIb / CD41 (ITGA2B) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx139599
tested applications
FCM

Description

CD41 Antibody is a Mouse Monoclonal against CD41.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Integrin Alpha IIb / CD41 (ITGA2B)
Host
Mouse
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Biotin
Isotype
IgG1
Clone ID
U468
Size 1
0.1 mg
Tested Applications
FCM
Buffer
PBS solution with 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8°C. Do not freeze.
Dry Ice
No
UniProt ID
P08514
Gene ID
3674
Alias
GT,GT1,GTA,CD41,GP2B,HPA3,CD41B,GPIIb,BDPLT2,BDPLT16,PPP1R93,Integrin alpha-Iib,GPalpha IIb (GPIIb),Platelet membrane glycoprotein IIb
Background
Antibody anti-ITGA2B
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

ITGA2B, also known as integrin alpha 2b or CD41, is a transmembrane glycoprotein that plays a central role in platelet adhesion and aggregation. It is primarily expressed on platelets and megakaryocytes. Together with integrin beta 3 (ITGB3), ITGA2B forms the αIIbβ3 integrin complex (also known as GPIIb/IIIa), which is the most abundant integrin on the surface of platelets and is crucial for blood clot formation (hemostasis). This receptor mediates platelet aggregation by binding to fibrinogen, von Willebrand factor (vWF), fibronectin, and other adhesive proteins during platelet activation. When platelets are stimulated, the αIIbβ3 complex undergoes a conformational change that allows it to bind its ligands and mediate platelet-platelet interactions.

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