Integrin Alpha IIb / CD41 (ITGA2B) Antibody

357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Integrin Alpha IIb / CD41 (ITGA2B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx145640
tested applications
ELISA, WB, IHC
Description
ITGA2B Antibody is a Rabbit Polyclonal against ITGA2B.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Integrin Alpha IIb / CD41 (ITGA2B) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by antigen affinity column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, WB, IHC |
Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
NCBI Accession | BC117443 |
Alias | GT,GT1,GTA,CD41,GP2B,HPA3,CD41B,GPIIb,BDPLT2,BDPLT16,PPP1R93,Integrin alpha-Iib,GPalpha IIb (GPIIb),Platelet membrane glycoprotein IIb |
Background | Antibody anti-ITGA2B |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ITGA2B, also known as integrin alpha 2b or CD41, is a transmembrane glycoprotein that plays a central role in platelet adhesion and aggregation. It is primarily expressed on platelets and megakaryocytes. Together with integrin beta 3 (ITGB3), ITGA2B forms the αIIbβ3 integrin complex (also known as GPIIb/IIIa), which is the most abundant integrin on the surface of platelets and is crucial for blood clot formation (hemostasis). This receptor mediates platelet aggregation by binding to fibrinogen, von Willebrand factor (vWF), fibronectin, and other adhesive proteins during platelet activation. When platelets are stimulated, the αIIbβ3 complex undergoes a conformational change that allows it to bind its ligands and mediate platelet-platelet interactions.
Related Products

APC Anti-Human CD41 (HIP8)
Ver Producto
Human ITGA2B (Integrin alpha-IIb) ELISA Kit
Ver Producto