Integrin Alpha-4 (ITGA4) Antibody (PE)
286€ (0.1 mg)
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name
Integrin Alpha-4 (ITGA4) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx140908
tested applications
FCM
Description
Integrin Alpha-4 (ITGA4) Antibody (PE) is a Rat Monoclonal against Integrin Alpha-4 (ITGA4).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Integrin Alpha-4 (ITGA4) |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2b Kappa |
| Clone ID | Z176 |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q00651 |
| Gene ID | 16401 |
| Alias | IA4,CD49D,Integrin alpha-4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha |
| Background | Antibody anti-ITGA4 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
Integrin subunit alpha 4 (ITGA4) is a critical member of the integrin family of cell surface receptors, which mediate cell-cell and cell-extracellular matrix (ECM) interactions. ITGA4 pairs with different beta subunits to form heterodimeric receptors that facilitate various biological processes, including immune cell migration, inflammation, tissue development, and cell adhesion. ITGA4 predominantly forms heterodimers with integrin beta 1 (ITGB1) to create the α4β1 integrin, also known as very late antigen-4 (VLA-4), and with integrin beta 7 (ITGB7) to form the α4β7 integrin. These integrins are particularly important in the immune system, where they mediate leukocyte adhesion and migration across blood vessels and into inflamed tissues.
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