Integrin Alpha 4 (ITGA4) Antibody
637€ (100 µl)
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Name
Integrin Alpha 4 (ITGA4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx113184
Tested Applications
ELISA, WB
Description
Integrin, Alpha 4 (Antigen Cd49D, Alpha 4 Subunit Of Vla-4 Receptor) Antibody is a Rabbit Polyclonal antibody against Integrin, Alpha 4 (Antigen Cd49D, Alpha 4 Subunit Of Vla-4 Receptor).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Integrin Alpha 4 (ITGA4) Immunogen: Human ITGA4. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13612 |
| Gene ID | 3676 |
| NCBI Accession | NP_000876.3 |
| OMIM | 192975 |
| Alias | IA4,CD49D,Integrin alpha-4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha |
| Background | Antibody anti-ITGA4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Integrin subunit alpha 4 (ITGA4) is a critical member of the integrin family of cell surface receptors, which mediate cell-cell and cell-extracellular matrix (ECM) interactions. ITGA4 pairs with different beta subunits to form heterodimeric receptors that facilitate various biological processes, including immune cell migration, inflammation, tissue development, and cell adhesion. ITGA4 predominantly forms heterodimers with integrin beta 1 (ITGB1) to create the α4β1 integrin, also known as very late antigen-4 (VLA-4), and with integrin beta 7 (ITGB7) to form the α4β7 integrin. These integrins are particularly important in the immune system, where they mediate leukocyte adhesion and migration across blood vessels and into inflamed tissues.
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