Integrin Alpha 3 (ITGA3) Antibody

Este producto es parte de ITGA3 - integrin subunit alpha 3
Integrin Alpha 3 (ITGA3) Antibody
221€ (50 µg)

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Name
Integrin Alpha 3 (ITGA3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx327844
Tested Applications
ELISA, WB

Description

ITGA3 Antibody is a Rabbit Polyclonal against ITGA3.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Integrin Alpha 3 (ITGA3)
Immunogen: Synthesized peptide derived from the Internal region of human Integrin α3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P26006
Gene ID
3675
Alias
JEB7,VL3A,CD49C,FRP-2,GAPB3,ILNEB,MSK18,VCA-2,VLA3a,GAP-B3,Integrin alpha-3,CD49 antigen-like family member C,Galactoprotein B3,VLA-3 subunit alpha
Background
Antibody anti-ITGA3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Integrin subunit alpha 3 (ITGA3) is part of the integrin family, which are heterodimeric transmembrane receptors crucial for mediating interactions between cells and the extracellular matrix (ECM). Integrins are essential for cell adhesion, migration, and signal transduction, contributing to various biological processes such as tissue repair, immune response, and embryonic development. ITGA3 pairs with integrin beta 1 (ITGB1) to form the α3β1 integrin, which serves as a receptor for laminin, fibronectin, and other ECM components, playing a vital role in cell adhesion and migration. ITGA3 is encoded by the ITGA3 gene, located on chromosome 17q21.33. The expression of ITGA3 is widespread, particularly in tissues such as epithelial cells, endothelial cells, and neurons. The α3β1 integrin is involved in important physiological processes like embryogenesis, angiogenesis, and wound healing, as well as in tumor metastasis and invasion in pathological conditions. In cancer biology, ITGA3 is often associated with tumor progression and can influence cellular invasiveness.

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