Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004091
tested applications
WB
Description
IMPDH2 Antibody is a Rabbit Polyclonal antibody against IMPDH2. This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Inosine 5'-Monophosphate Dehydrogenase 2 (IMPDH2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P12268 |
| Gene ID | 3615 |
| NCBI Accession | NP_000875.2 |
| Background | Antibody anti-IMPDH2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
Human IMPDH2 (Inosine 5'-Monophosphate Dehydrogenase 2) ELISA Kit
Ver Producto
Rat IMPDH2 (Inosine 5'-Monophosphate Dehydrogenase 2) ELISA Kit
Ver Producto
IMPDH2 antibody
Catalyzes the conversion of inosine 5'-phosphate(IMP) to xanthosine 5'-phosphate(XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Ver Producto