Indian Hedgehog Protein (IHH) Antibody
312€ (60 µl)
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935106861
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name
Indian Hedgehog Protein (IHH) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005080
tested applications
WB
Description
IHH Antibody is a Rabbit Polyclonal antibody against IHH. This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Indian Hedgehog Protein (IHH) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14623 |
| Gene ID | 3549 |
| NCBI Accession | NP_002172.2 |
| Background | Antibody anti-IHH |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Intercellular signal essential for a variety of patterning events during development. Binds to the patched(PTC) receptor, which functions in association with smoothened(SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein(PTHRP)(By similarity).
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