Human Vascular endothelial growth factor receptor 2 / FLK1 (KDR) ELISA Kit
565.5€ (96 tests)
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935106861
info@markelab.com
name
Human Vascular endothelial growth factor receptor 2 / FLK1 (KDR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx252692
tested applications
ELISA
Description
Human Vascular endothelial growth factor receptor 2 / FLK1 (KDR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Vascular endothelial growth factor receptor 2 / FLK1 (KDR) concentrations in serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Vascular endothelial growth factor receptor 2 / FLK1 (KDR) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P35968 |
| OMIM | 191306 |
| Alias | FLK1,CD309,VEGFR,VEGFR2,VEGFR-2,Protein-tyrosine kinase receptor flk-1,Fetal liver kinase 1,Vascular endothelial growth factor receptor 2 |
| Background | Elisa kits for KDR |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
KDR, also known as vascular endothelial growth factor receptor 2 (VEGFR-2), is a critical protein in the regulation of angiogenesis and vascular development. This receptor tyrosine kinase (RTK) is encoded by the KDR gene located on chromosome 4q12 in humans. KDR is a member of the VEGF receptor family, which plays an essential role in the processes of vasculogenesis and angiogenesis by mediating the cellular responses to the vascular endothelial growth factor (VEGF). The VEGF family consists of several ligands, with VEGF-A being the primary ligand for KDR. KDR is predominantly expressed in endothelial cells, where it regulates vascular permeability, endothelial cell proliferation, migration, and survival. Due to its pivotal role in vascular biology, KDR has been extensively studied in the context of cancer, where angiogenesis is a crucial process for tumor growth and metastasis. KDR's involvement in pathological angiogenesis makes it a significant target for anti-angiogenic therapies in cancer treatment. Moreover, it has implications in other diseases characterized by abnormal vascular growth, such as age-related macular degeneration and rheumatoid arthritis.
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