Human Vascular Endothelial Growth Factor C (VEGFC) Protein

Este producto es parte de VEGFC - Vascular Endothelial Growth Factor C
Human Vascular Endothelial Growth Factor C (VEGFC) Protein
234€ (5 µg)

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Name
Human Vascular Endothelial Growth Factor C (VEGFC) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx262066
Tested Applications
SDS-PAGE

Description

VEGFC Protein is a recombinant protein produced by transfected human cells (HEK293 cells) is a single polypeptide chain containing 204 amino acids (32-227). VEGFC is fused to an 8 amino acid His-tag at C-terminus nad purified by proprietary chromatographic techniques.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Vascular Endothelial Growth Factor C (VEGFC)
Host
Human
Assay Type
Activity: Not tested
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Lyophilized
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
P49767
Alias
VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein
Background
Protein VEGFC
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking

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