Human Vascular Endothelial Growth Factor C (VEGFC) Protein
234€ (5 µg)
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935106861
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name
Human Vascular Endothelial Growth Factor C (VEGFC) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262066
tested applications
SDS-PAGE
Description
VEGFC Protein is a recombinant protein produced by transfected human cells (HEK293 cells) is a single polypeptide chain containing 204 amino acids (32-227). VEGFC is fused to an 8 amino acid His-tag at C-terminus nad purified by proprietary chromatographic techniques.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Vascular Endothelial Growth Factor C (VEGFC) |
| Host | Human |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P49767 |
| Alias | VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein |
| Background | Protein VEGFC |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking
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