Human Vascular Cell Adhesion Molecule 1 (VCAM1) Protein

Human Vascular Cell Adhesion Molecule 1 (VCAM1) Protein

Pida mas información

935106861

info@markelab.com

Precio

225€ (2 µg)

proveedor

Abbexa

reference

abx680059

Tested Applications

SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Vascular Cell Adhesion Molecule 1 (VCAM1) Protein is a recombinant protein produced in Sf9, Baculovirus cells.

Background

Vascular cell adhesion protein 1, also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106), is a human protein encoded by the VCAM1 gene. VCAM-1 plays a critical role in interacting with the integrin very late antigen-4 (VLA4).VCAM-1 is responsible for facilitating the adhesion of various immune cells, including lymphocytes, monocytes, eosinophils, and basophils, to the endothelial blood vessel. Additionally, it plays a vital role in signal transduction between leukocytes and endothelial cells, and it has been implicated in the development of conditions such as atherosclerosis and rheumatoid arthritis. Ectodomain release of VCAM-1 is observed in various situations and is often mediated by enzymes like matrix metalloproteinases (MMPs) and ADAMs (A Disintegrin and Metalloproteinase). This release can be triggered by external factors such as calcium ionophores, cytokines, and growth factors. VCAM-1 is also known by the alias CD106

Características del producto

category

Proteins and Peptides


origin

Human


host

Insect


immunogen target

Vascular Cell Adhesion Molecule 1 (VCAM1)


host

Insect


conjugation

Unconjugated


form

Liquid


tested applications

SDS-PAGE


size 1

2 µg


size 2

10 µg


size 3

1 mg


expression

Recombinant


purity

> 90% (SDS-PAGE)


or code

VCAM1


dry ice

No


availability

Shipped within 5-10 working days.


alias

V-CAM 1,VCAM-1,INCAM-100,CD106


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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