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Human Vascular Cell Adhesion Molecule 1 (VCAM1) Protein
proveedor
Abbexareference
abx069622Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) is a recombinant Human protein produced in E. coli using Prokaryotic expression.
Background
Vascular cell adhesion protein 1, also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106), is a human protein encoded by the VCAM1 gene. VCAM-1 plays a critical role in interacting with the integrin very late antigen-4 (VLA4).VCAM-1 is responsible for facilitating the adhesion of various immune cells, including lymphocytes, monocytes, eosinophils, and basophils, to the endothelial blood vessel. Additionally, it plays a vital role in signal transduction between leukocytes and endothelial cells, and it has been implicated in the development of conditions such as atherosclerosis and rheumatoid arthritis. Ectodomain release of VCAM-1 is observed in various situations and is often mediated by enzymes like matrix metalloproteinases (MMPs) and ADAMs (A Disintegrin and Metalloproteinase). This release can be triggered by external factors such as calcium ionophores, cytokines, and growth factors. VCAM-1 is also known by the alias CD106
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Vascular Cell Adhesion Molecule 1 (VCAM1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
VCAM1
dry ice
No
availability
Shipped within 5-12 working days.
alias
V-CAM 1,VCAM-1,INCAM-100,CD106
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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