Human Uromodulin (UMOD) Protein
234€ (2 µg)
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name
Human Uromodulin (UMOD) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073760
tested applications
SDS-PAGE
Description
Human Uromodulin (UMOD) Protein is a glycosylated polypeptide isolated from Human urine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Uromodulin (UMOD) |
| Host | Human |
| Assay Type | Activity: Not tested |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Observed MW | 80 kDa |
| Purity | > 95% (SDS-PAGE) |
| Purification | Filtered (0.4 µm) prior to lyophilization. |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Not applicable. |
| Availability | Shipped within 5-10 working days. |
| Storage | Storage: Store lyophilized at 2-8°C. Do not freeze. Stability: Stable lyophilized at room temperature for up to 3 weeks. |
| Dry Ice | No |
| UniProt ID | P07911 |
| Gene ID | 7369 |
| OMIM | 162000 |
| Background | Protein UMOD |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water to a concentration of approximately 0.5 mg/ml. Ensure that the product is fully dissolved before use. Please note that this product is not sterile, filtration using an appropriate sterile filter should be carried out before using the product in cell culture. Concentration: Prior to lyophilization: 0.5 mg/ml |
Descripción
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UMOD antibody
Uromodulin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases.(PMID: 21654721)
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