Human Uncharacterized protein C9orf66 (DOCK8-AS1) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Uncharacterized protein C9orf66 (DOCK8-AS1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx506737
tested applications
ELISA
Description
Human Uncharacterized protein C9orf66 (DOCK8-AS1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Uncharacterized protein C9orf66 (DOCK8-AS1) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Uncharacterized protein C9orf66 (DOCK8-AS1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5T8R8 |
| Alias | HEL-205,HIES2,MRD2,ZIR8 |
| Background | Elisa kits for DOCK8 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DOCK8 is a GEF primarily activating Rac1 and Cdc42, critical for actin cytoskeleton regulation, immune cell migration, and synapse formation. It is essential for lymphocyte survival, intercellular adhesion, and immune synapse organization. DOCK8 deficiency causes DOCK8 immunodeficiency syndrome, characterized by recurrent infections, allergies, and autoimmunity. It interacts with proteins like WASP and ELMO to promote immune cell migration and T-cell activation. DOCK8 is highly expressed in hematopoietic cells, particularly T and B cells. Dysregulation impairs lymphocyte trafficking and survival, contributing to immune dysfunction. Studies in knockout models show defects in T-cell proliferation, migration, and immune surveillance.
Related Products
anti- DOCK8 antibody
Potential guanine nucleotide exchange factor(GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP(By similarity).
Ver Producto
Recombinant Human DOCK8
Ver Producto
Docking Protein 8 (DOCK8) Antibody
Dedicator Of Cytokinesis 8 Antibody is a Rabbit Polyclonal antibody against Dedicator Of Cytokinesis 8.
Ver Producto