Human Ubiquitin-Conjugating Enzyme E2 T (UBE2T) Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Ubiquitin-Conjugating Enzyme E2 T (UBE2T) protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Ubiquitin-Conjugating Enzyme E2 T (UBE2T) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Val197 Tag: N-terminal 6 His tag |
| Origin | Human |
| Observed MW | 24.7 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. Shelf Life: 6 months. |
| Dry Ice | No |
| UniProt ID | Q9NPD8 |
| Background | Protein UBE2T |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Related Products
UBE2T antibody
The ubiquitin(Ub)-mediated protein degradation pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub to specific protein substrates. The first step requires ATP-dependent activation of the C-terminus of Ub and the assembly of multi-Ubs by Ub-activating enzyme E1. The ubiquitin-conjugating enzyme E2, catalytic(UBCc) domain, is then conjugated to Ubs, through a thiol-ester linkage between a conserved cysteine and the C-terminus of Ub, to generate an intermediate Ub-E2 complex. Then the E3, a ligase, catalyzes the transfer of Ub from E2 to the appropriate substrate. This pathway regulates many fundamental cellular processes. There are also other E2s which form thiol-ester linkages without the use of E3s as well as several UBC homologs(TSG101, Mms2, Croc-1 and similar proteins), which lack the active site cysteine essential for ubiquitination and appear to function in DNA repair pathways.
Ver Producto
Recombinant Human UBE2T
Ver Producto
Ubiquitin Conjugating Enzyme E2 T (UBE2T) Antibody
Rabbit polyclonal antibody against UBE2T protein. Immunogen region is Internal.
Ver Producto