Human U4/U6.U5 tri-snRNP-associated protein 1 (SART1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human U4/U6.U5 tri-snRNP-associated protein 1 (SART1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx383029
tested applications
ELISA
Description
Human U4/U6.U5 tri-snRNP-associated protein 1 (SART1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SART1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | U4/U6.U5 tri-snRNP-associated protein 1 (SART1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O43290 |
| Gene ID | 9092 |
| OMIM | 605941 |
| Alias | Ara1,HAF,HOMS1,SART1259,SNRNP110,Snu66,SNU66 homolog,U4/U6.U5 tri-snRNP-associated protein 1 |
| Background | Elisa kits for SART1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP (SART1) is a key protein involved in pre-mRNA splicing, a critical step in eukaryotic gene expression SART1 facilitates the recruitment of the U4/U6.U5 tri-snRNP complex to the spliceosome during the spliceosome assembly process, ensuring accurate splicing of pre-mRNA into mature mRNA It is essential for maintaining cellular RNA homeostasis and regulating alternative splicing events that diversify the proteome SART1 also participates in cellular stress responses, where it modulates RNA processing and repair pathways Dysregulation of SART1 has been linked to cancer, particularly in tumor cells where aberrant splicing events promote oncogenic gene expression and survival pathways Additionally, SART1 has roles in immune system function, as it interacts with viral RNAs during infections, contributing to the host antiviral response Its importance in RNA splicing, gene regulation, and disease underscores its essential role in cellular and molecular biology
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