Human Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits TNFRSF14
proveedor
Abbexareference
abx252467Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tumor necrosis factor receptor superfamily member 14 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TNFRSF14, also known as herpesvirus entry mediator (HVEM), is a member of the tumor necrosis factor receptor superfamily (TNFRSF). Expressed broadly on hematopoietic and non-hematopoietic cells, TNFRSF14 is a transmembrane receptor involved in regulating immune responses. It is a critical component in balancing immune activation and suppression, particularly in T cell regulation, innate immunity, and inflammation. TNFRSF14 interacts with several ligands, including LIGHT (TNFSF14), BTLA (B and T lymphocyte attenuator), and CD160, which engage the receptor in activating or inhibitory roles depending on the context. Due to its role in immune regulation, TNFRSF14 is significant in autoimmune diseases, cancer, and infectious diseases. For example, in autoimmune diseases like multiple sclerosis, TNFRSF14 signaling can contribute to disease pathology through immune cell activation and inflammation. In oncology, TNFRSF14 can act as an immune checkpoint, modulating anti-tumor immunity, making it a target for potential immunotherapy interventions.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
< 15 pg/ml
assay type
Competitive
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Tumor necrosis factor receptor superfamily member 14,TR2,ATAR,HVEA,HVEM; CD270,LIGHTR,Herpes virus entry mediator A,Tumor necrosis factor receptor-like 2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
TNFRSF14
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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