Human Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14) ELISA Kit

Este producto es parte de TNFRSF14 - TNF receptor superfamily member 14
Human Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits TNFRSF14

proveedor

Abbexa

reference

abx252467

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tumor necrosis factor receptor superfamily member 14 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TNFRSF14, also known as herpesvirus entry mediator (HVEM), is a member of the tumor necrosis factor receptor superfamily (TNFRSF). Expressed broadly on hematopoietic and non-hematopoietic cells, TNFRSF14 is a transmembrane receptor involved in regulating immune responses. It is a critical component in balancing immune activation and suppression, particularly in T cell regulation, innate immunity, and inflammation. TNFRSF14 interacts with several ligands, including LIGHT (TNFSF14), BTLA (B and T lymphocyte attenuator), and CD160, which engage the receptor in activating or inhibitory roles depending on the context. Due to its role in immune regulation, TNFRSF14 is significant in autoimmune diseases, cancer, and infectious diseases. For example, in autoimmune diseases like multiple sclerosis, TNFRSF14 signaling can contribute to disease pathology through immune cell activation and inflammation. In oncology, TNFRSF14 can act as an immune checkpoint, modulating anti-tumor immunity, making it a target for potential immunotherapy interventions.

Características del producto

category

ELISA Kits


immunogen target

Tumor Necrosis Factor Receptor Superfamily Member 14 / CD270 (TNFRSF14)


reactivity

Human


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

< 15 pg/ml


assay type

Competitive


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

Tumor necrosis factor receptor superfamily member 14,TR2,ATAR,HVEA,HVEM; CD270,LIGHTR,Herpes virus entry mediator A,Tumor necrosis factor receptor-like 2


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

TNFRSF14


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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