Human Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) ELISA Kit
559€ (96 tests)
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935106861
info@markelab.com
name
Human Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx521076
tested applications
ELISA
Description
Human Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9UBN6 |
| Alias | Tumor necrosis factor receptor superfamily member 10D,DCR2,CD264,TRUNDD,TRAILR4,TRAIL-R4,Decoy receptor 2,TNF-related apoptosis-inducing ligand receptor 4,(TRAIL receptor 4 |
| Background | Elisa kits for TNFRSF10D |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TNFRSF10D, also known as TRAIL-R4 or DcR2 (Decoy Receptor 2), is a member of the tumor necrosis factor receptor superfamily, specifically binding TRAIL (TNF-related apoptosis-inducing ligand). Unlike apoptosis-inducing TRAIL receptors, such as TNFRSF10A (TRAIL-R1) and TNFRSF10B (TRAIL-R2), TNFRSF10D functions primarily as a “decoy” receptor. It plays a modulatory role by binding TRAIL and potentially preventing TRAIL-induced apoptosis in non-transformed cells. TNFRSF10D is unique among TRAIL receptors in that, while it possesses an intracellular tail with a truncated death domain, it lacks the full ability to transduce apoptotic signals. This feature gives it a protective function, especially in healthy cells where it modulates apoptosis sensitivity. TNFRSF10D is expressed in various normal tissues and has been implicated in protecting these tissues from unwanted TRAIL-mediated apoptosis. It is a subject of considerable interest in the field of cancer biology and immune modulation, as its expression pattern and function influence both tumor immunity and potential cancer cell resistance to TRAIL-based therapies.
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