Human Transmembrane Protease Serine 2 (TMPRSS2) Protein

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546€ (100 µg)

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935106861
info@markelab.com
name
Human Transmembrane Protease Serine 2 (TMPRSS2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620179
tested applications
ELISA, WB, SDS-PAGE

Description

Human Transmembrane Protease Serine 2 (TMPRSS2) Protein is a recombinant Human protein produced in a Mammalian cell expression system.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Transmembrane Protease Serine 2 (TMPRSS2)
Host
Mammalian cells
Assay Type
Activity: Not tested
Sequence Fragment: Trp106-Arg255
Tag: N-terminal Fc tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 44.19 kDa
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
O15393
Background
Protein TMPRSS2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Reconstitute in sterile water to produce a stock solution.

Descripción

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This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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