Human Transmembrane Protease, Serine 2 (TMPRSS2) Protein
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Description
Human Transmembrane Protease, Serine 2 (TMPRSS2) Protein is a recombinant Human protein expressed in E. coli.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Transmembrane Protease, Serine 2 (TMPRSS2) |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: Calculated MW: 25.65 kDa Sequence Fragment: Ser284-Gly492 Tag: His tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.5. |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | O15393 |
| Background | Protein TMPRSS2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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TMPRSS2 antibody
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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