Human Transforming Growth Factor Beta 3 (TGFb3) Protein
767€ (50 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Transforming Growth Factor Beta 3 (TGFb3) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx655844
Tested Applications
WB, SDS-PAGE
Description
Human Transforming Growth Factor Beta 3 (TGFb3) is an active Human protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Transforming Growth Factor Beta 3 (TGFb3) |
| Assay Type | Activity: Active Sequence Fragment: His274-Ala372 |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 16.4 kDa Observed MW (SDS-PAGE): 17 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10600 |
| Alias | ARVD,ARVD1,LDS5,RNHF,TGF-beta3,Latency-associated peptide LAP,Transforming growth factor beta-3 |
| Background | Protein TGFB3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
TGFB3 is another member of the TGF-β family that is predominantly involved in embryonic development, tissue remodeling, and wound healing. TGFB3 regulates processes such as epithelial-mesenchymal transition (EMT), extracellular matrix (ECM) deposition, and immune suppression. It is highly expressed during palatogenesis, craniofacial development, and lung morphogenesis, where it plays an essential role in cell signaling and tissue architecture. TGFB3 facilitates proper scar formation and tissue repair by modulating fibroblast activation and ECM production while reducing excessive fibrosis. In cancer, TGFB3 contributes to tumor progression by inducing EMT and promoting metastatic dissemination. Mutations or dysregulation of TGFB3 are associated with cleft palate, cardiovascular abnormalities, and fibrotic diseases. Knockout models reveal impaired wound healing, disrupted tissue morphogenesis, and craniofacial defects, highlighting TGFB3’s role in tissue development, regeneration, and fibrotic regulation.
Productos relacionados
Transforming Growth Factor Beta 3 (TGFB3) Antibody
TGFB3 Antibody is a Rabbit Polyclonal Antibody against TGFB3.…
Ver producto
Transforming Growth Factor Beta-3 (TGFB3) Antibody
Rabbit polyclonal antibody against TGF beta 3 protein. Immunogen region is Internal.…
Ver producto
Human Transforming Growth Factor Beta 3 (TGFb3) Protein
Human Transforming Growth Factor Beta 3 (TGFb3) Protein is a recombinant Human protein expressed in E. coli.…
Ver producto