Human TNFRSF4/OX40 (Tumor necrosis factor receptor superfamily member 4) ELISA Kit
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name
Human TNFRSF4/OX40 (Tumor necrosis factor receptor superfamily member 4) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH0310
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 7.8-500pg/ml |
| Sensitivity | 4.688pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P43489 |
| Alias | OX40,ACT35,CD134,IMD16,TXGP1L,OX40L receptor,TAX transcriptionally-activated glycoprotein 1 receptor |
| Background | Elisa kits for TNFRSF4 |
| Status | RUO |
TNFRSF4, commonly known as OX40 (CD134), is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is an important costimulatory molecule expressed on T cells, specifically induced upon T cell activation. TNFRSF4 is known for its involvement in regulating immune responses, especially in T-cell proliferation, survival, and memory formation. As an immune-regulatory receptor, it primarily interacts with its ligand, OX40L (TNFSF4), which is expressed on antigen-presenting cells (APCs), such as dendritic cells, B cells, and macrophages. OX40’s role in immune modulation is significant because it amplifies T-cell responses during both acute infections and in chronic immune responses, such as autoimmune diseases and cancer. By sustaining T-cell activation and enhancing immune memory, OX40 has become a central target in immunotherapy research, especially in the contexts of cancer immunotherapy and autoimmune diseases. Its ability to promote prolonged immune responses also makes it a critical regulator in various immune-related diseases, where modulation of OX40-OX40L interactions can potentially benefit patient outcomes.
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