Human TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) Protein
234€ (5 µg)
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935106861
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name
Human TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx261872
tested applications
SDS-PAGE
Description
sFas Receptor Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | TNF Receptor Superfamily Member 6 / CD95 / TNFRSF6 (FAS) |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE and RP-HPLC) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P25445 |
| Alias | APT1,CD95,FAS1,APO-1,FASTM,ALPS1A,TNFRSF6,Apo-1 antigen,Apoptosis-mediating surface antigen FAS,FASLG receptor |
| Background | Protein FAS |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Tumor necrosis factor receptor superfamily member 6 (FAS), also known as CD95, is a cell surface receptor involved in the regulation of apoptosis through the extrinsic pathway FAS belongs to the TNF receptor family and triggers apoptosis upon binding with its ligand, FASL This interaction activates the caspase cascade, leading to programmed cell death FAS-mediated apoptosis plays a critical role in immune system regulation, particularly in eliminating autoreactive T-cells during immune tolerance and in regulating the survival of activated immune cells In addition to immune regulation, FAS signaling is involved in tumor progression, where altered expression of FAS or its ligand can either promote or inhibit cancer cell survival In many cancers, FAS expression is dysregulated, contributing to resistance to apoptosis and enabling tumor cell evasion from immune surveillance FAS has also been implicated in autoimmune diseases, where inappropriate activation or inhibition of FAS signaling can lead to tissue damage and chronic inflammation
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