Human TNF receptor-associated factor 7 (TRAF7) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TRAF7
proveedor
Abbexareference
abx383898Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human TNF receptor-associated factor 7 (TRAF7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TRAF7 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TRAF7 is a unique member of the TRAF family that functions as both a signaling adaptor protein and an E3 ubiquitin ligase. Unlike other TRAFs, TRAF7 primarily regulates noncanonical pathways, including MAPK, NF-κB, and apoptosis signaling, through its role in ubiquitination and protein degradation. TRAF7 interacts with TNF receptor family members, Toll-like receptors (TLRs), and transcription factors like p53 to regulate inflammation, cell survival, and apoptosis. It is widely expressed in epithelial tissues, immune cells, and the nervous system, where it plays roles in tissue homeostasis, cellular stress responses, and immune regulation. Dysregulation of TRAF7 has been associated with cancers, including meningiomas and sarcomas, where it affects cell proliferation and survival. Functional studies demonstrate its dual role in promoting cell survival and apoptosis, depending on cellular context, highlighting its significance in signaling regulation, ubiquitination, and tumor suppression.
Características del producto
category
ELISA Kits
immunogen target
TNF receptor-associated factor 7 (TRAF7)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
RFWD1,RNF119,CAFDADD,RING finger protein 119,RING-type E3 ubiquitin transferase TRAF7
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TRAF7
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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