Human TNF receptor-associated factor 7 (TRAF7) ELISA Kit

Este producto es parte de TRAF - TNF receptor associated factor
Human TNF receptor-associated factor 7 (TRAF7) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TRAF7

proveedor

Abbexa

reference

abx383898

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human TNF receptor-associated factor 7 (TRAF7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TRAF7 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TRAF7 is a unique member of the TRAF family that functions as both a signaling adaptor protein and an E3 ubiquitin ligase. Unlike other TRAFs, TRAF7 primarily regulates noncanonical pathways, including MAPK, NF-κB, and apoptosis signaling, through its role in ubiquitination and protein degradation. TRAF7 interacts with TNF receptor family members, Toll-like receptors (TLRs), and transcription factors like p53 to regulate inflammation, cell survival, and apoptosis. It is widely expressed in epithelial tissues, immune cells, and the nervous system, where it plays roles in tissue homeostasis, cellular stress responses, and immune regulation. Dysregulation of TRAF7 has been associated with cancers, including meningiomas and sarcomas, where it affects cell proliferation and survival. Functional studies demonstrate its dual role in promoting cell survival and apoptosis, depending on cellular context, highlighting its significance in signaling regulation, ubiquitination, and tumor suppression.

Características del producto

category

ELISA Kits


immunogen target

TNF receptor-associated factor 7 (TRAF7)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

RFWD1,RNF119,CAFDADD,RING finger protein 119,RING-type E3 ubiquitin transferase TRAF7 


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TRAF7


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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