Human TNF receptor-associated factor 1 (TRAF1) ELISA Kit

Este producto es parte de TRAF - TNF receptor associated factor
Human TNF receptor-associated factor 1 (TRAF1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TRAF1

proveedor

Abbexa

reference

abx383893

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human TNF receptor-associated factor 1 (TRAF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TRAF1 concentrations in serum, plasma and other biological fluids.


Background

TRAF1 is an adaptor protein in the tumor necrosis factor receptor (TNFR) superfamily signaling pathways, playing a role in regulating NF-κB and MAPK activation, apoptosis, and immune responses. TRAF1 interacts with TNFR1, TNFR2, and other members of the TNF receptor family to mediate downstream signaling, promoting survival and inflammatory responses. TRAF1 is predominantly expressed in immune cells, including T cells, B cells, and macrophages, where it modulates cytokine production and apoptosis inhibition. It forms heterodimers with TRAF2 to regulate receptor complex formation and downstream signal transduction. Dysregulation of TRAF1 contributes to autoimmune diseases, chronic inflammation, and certain cancers by altering TNF signaling and immune responses. Knockdown studies show defects in cytokine production, reduced NF-κB activation, and increased susceptibility to apoptosis, underscoring its role in balancing immune homeostasis and cell survival pathways.

Características del producto

category

ELISA Kits


immunogen target

TNF receptor-associated factor 1 (TRAF1)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

TRAF-1,TRAF1,EBI6, MGC:10353, TNF receptor associated factor 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TRAF1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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