Human Thyrotropin-Releasing Hormone Receptor (TRHR) ELISA Kit

Este producto es parte de TRHR - Thyrotropin-Releasing Hormone Receptor
Human Thyrotropin-Releasing Hormone Receptor (TRHR) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits TRHR

proveedor

Abbexa

reference

abx385472

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Thyrotropin-Releasing Hormone Receptor (TRHR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human TRHR concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

The Thyrotropin-Releasing Hormone Receptor (TRHR) is a G protein-coupled receptor (GPCR) that is activated by thyrotropin-releasing hormone (TRH), a peptide hormone responsible for regulating the secretion of thyroid-stimulating hormone (TSH) from the pituitary gland. TRHR is primarily expressed in the anterior pituitary, where it plays a critical role in the regulation of thyroid function by stimulating the release of TSH. Upon activation, TRHR couples to Gq proteins, stimulating phospholipase C (PLC) and increasing intracellular calcium levels, which in turn promotes the release of TSH and the synthesis of thyroid hormones (T3 and T4). TRHR also plays a role in regulating metabolic processes, growth, and development. Dysregulation of TRHR signaling is implicated in disorders such as hypothyroidism, hyperthyroidism, and thyroid tumors. Targeting TRHR with agonists or antagonists can be useful for managing thyroid-related conditions and regulating thyroid hormone production.

Características del producto

category

ELISA Kits


immunogen target

Thyrotropin-Releasing Hormone Receptor (TRHR)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

TRHR,TRH receptor,thyroliberin receptor,TRH-R,TRH-R1,CHNG7


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

TRHR


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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