Human THRA (Thyroid hormone receptor alpha) ELISA Kit

Este producto es parte de THR - thyroid hormone receptor
Human THRA (Thyroid hormone receptor alpha) ELISA Kit
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Name
Human THRA (Thyroid hormone receptor alpha) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH2004
Tested Applications
ELISA

Documentos del producto

Instrucciones
Descargar
Data sheet

Especificaciones del producto

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
1.563-100mIU/ml
Sensitivity
0.938mIU/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P10827
Alias
AR7,EAR7,ERBA,ERBA1,NR1A1,THRA1,THRA2,c-erbA,ERB-T-1,Tralpha,THRalpha,TRalpha1,TRalpha2,c-ERBA-1,THRalpha1,THRalpha2,Nuclear receptor subfamily 1 group A member 1,V-erbA-related protein 7
Background
Elisa kits for THRA
Status
RUO

Background

Thyroid hormone receptor alpha (THRA) is a nuclear receptor that mediates the effects of thyroid hormones (T3 and T4) by regulating gene expression THRA exists in multiple isoforms, which are generated through alternative splicing and have tissue-specific functions The receptor plays a crucial role in the development, growth, and metabolism of various tissues, including the brain, heart, and muscles THRA regulates cellular processes such as metabolism, thermogenesis, and lipid metabolism by influencing the transcription of target genes involved in these pathways The receptor also has a vital role in the development of the nervous system, particularly during fetal and postnatal development Mutations in THRA can lead to various thyroid-related disorders, including resistance to thyroid hormone (RTH), where tissues become less responsive to thyroid hormones, resulting in elevated thyroid hormone levels and metabolic disturbances Additionally, THRA dysregulation has been implicated in certain cancers, where altered thyroid hormone signaling can contribute to tumor growth and progression

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