Human Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3) Enzyme

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234€ (5 µg)

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935106861
info@markelab.com
name
Human Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3) Enzyme
category
Proteins and Peptides
provider
Abbexa
reference
abx073560
tested applications
SDS-PAGE

Description

Peroxiredoxin-3 is a recombinant enzyme.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3)
Host
E. coli
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Origin
Human
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Storage
Store at 4 °C if the entire vial will be used within 4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P30048
Background
Protein PRDX3
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

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