Human Testin (TES) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Testin (TES) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251041
tested applications
ELISA
Description
Human Testin (TES) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Testin (TES) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Testin (TES) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Competitive |
| Test Range | 0.625 ng/ml - 40 ng/ml |
| Sensitivity | < 0.22 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9UGI8 |
| Alias | TESS,TESS-2 |
| Background | Elisa kits for TES |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TES is a tumor suppressor protein that belongs to the LIM domain-containing family, functioning in actin cytoskeletal organization, cell adhesion, and signaling regulation. TES interacts with focal adhesion proteins and actin-binding molecules to regulate cellular processes such as cell spreading, migration, and morphology. It acts as a scaffolding protein at focal adhesions, mediating interactions between the actin cytoskeleton and signaling molecules to maintain cell adhesion and structural integrity. TES is also involved in transcriptional regulation by interacting with nuclear proteins, including transcription factors, to control gene expression associated with cell growth and differentiation. Downregulation of TES is commonly observed in cancers, where its loss disrupts cytoskeletal organization and promotes tumor progression, metastasis, and reduced cell adhesion. Knockdown studies reveal increased cell motility, reduced cell adhesion, and enhanced invasive capacity, emphasizing TES’s critical role in maintaining cytoskeletal stability, suppressing tumor growth, and regulating cellular architecture.
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