Human T-lymphocyte activation antigen CD80 / B7-1 (CD80) Protein

Este producto es parte de CD80 molecule
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533€ (100 µg)

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935106861
info@markelab.com
name
Human T-lymphocyte activation antigen CD80 / B7-1 (CD80) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691808
tested applications
SDS-PAGE

Description

Human CD80 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the extracellular domain (Met 1-Asn 242) of human B7-1 (NP_005182.1) precursor was fused with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
CD80
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: 25.4 kDa
Sequence Fragment: Met1-Asn242
Tag: C-terminal His tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
100 µg
Size 2
200 µg
Form
 
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NP_005182.1
Alias
B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80
Background
Protein CD80
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.

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