Human T-lymphocyte activation antigen CD80 / B7-1 (CD80) Protein

Este producto es parte de CD80 molecule
Product Graph
312€ (20 µg)

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935106861
info@markelab.com
name
Human T-lymphocyte activation antigen CD80 / B7-1 (CD80) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690059
tested applications
SDS-PAGE

Description

Human Activation B7-1 antigen Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Activation B7-1 antigen is produced by our Mammalian expression system and the target gene encoding Val35-Asn242 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Activation B7-1 antigen
Host
Human
Origin
Human
Observed MW
Molecular Weight: 24.7 kDa
Sequence Fragment: Met1-Asn242
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
NCBI Accession
NP_005182.1
Alias
B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80
Background
Protein CD80
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.

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