Human T-Cell Surface Glycoprotein CD5 (CD5) Protein
Pida mas información
935106861
info@markelab.com
Precio
221€ (10 µg)
Protein CD5
proveedor
Abbexareference
abx168765Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human CD5 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
The CD5 molecule is a type I transmembrane glycoprotein primarily expressed on the surface of T cells and a subset of B cells known as B1a cells. CD5 functions as an immunomodulatory receptor, playing a critical role in T-cell activation, immune tolerance, and B-cell signaling. Its primary role is in regulating immune responses by controlling the threshold of antigen receptor signaling in both T and B cells. CD5 is also involved in maintaining the delicate balance between immune activation and immune tolerance, which prevents autoimmune responses while ensuring effective immunity. CD5 belongs to the scavenger receptor cysteine-rich (SRCR) superfamily of receptors, a group of molecules known to be involved in diverse biological functions, including immunity, apoptosis, and cellular adhesion. CD5 is especially notable for its role as a negative regulator of T-cell receptor (TCR) and B-cell receptor (BCR) signaling. This regulatory capacity makes CD5 crucial in maintaining immune homeostasis.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
T-Cell Surface Glycoprotein CD5 (CD5)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 65.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln19-Ser336 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CD5
dry ice
No
availability
Shipped within 5-7 working days.
alias
T1,LEU1,T-cell surface glycoprotein CD5,Lymphocyte antigen T1/Leu-1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
anti- CD5 antibody
proveedor
FineTestreference
FNab01487Tested Applications
ELISA, WB,IHC,IP,IFreactivity
human,mousestatus
RUOclonality
polyclonalMay act as a receptor in regulating T-cell proliferation.
Precio a consultar
Ver másT-Cell Surface Glycoprotein CD5 (CD5) Antibody
proveedor
Abbexareference
abx006847Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalCD5 Antibody is a Rabbit Polyclonal Antibody against CD5.
195€ (20 µl)
Ver másT-Cell Surface Glycoprotein CD5 (CD5) Antibody
proveedor
Abbexareference
abx011660Tested Applications
ELISA, WB, FCMreactivity
Humanstatus
RUOclonality
MonoclonalThe human cd5 gene has two alternative exons 1: exon 1A (E1A) which encodes the full-length (FL) CD5 protein and exon 1B...
383.5€ (100 µl)
Ver más