Human T-Cell Surface Glycoprotein CD1a (CD1A) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits CD1A
proveedor
Abbexareference
abx386383Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human T-Cell Surface Glycoprotein CD1a (CD1A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human T-cell Surface Glycoprotein CD1a (CD1A) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD1a Molecule (CD1A) is a member of the CD1 family of glycoproteins involved in presenting lipid and glycolipid antigens to T cells. Expressed predominantly on the surface of dendritic cells, Langerhans cells, and thymocytes, CD1A plays a vital role in the immune system by bridging innate and adaptive immunity. Structurally, CD1A is similar to major histocompatibility complex (MHC) class I molecules but specializes in binding lipids and presenting them to a unique subset of T cells, particularly natural killer T (NKT) cells. This interaction is critical for initiating immune responses against certain pathogens, such as Mycobacterium tuberculosis and fungi, that contain unique lipid antigens. CD1A's role extends to the regulation of skin immunity, given its high expression in Langerhans cells within the epidermis. Dysregulation or altered expression of CD1A has been implicated in autoimmune disorders, certain cancers, and inflammatory skin diseases, such as psoriasis. It is also a marker used in histopathology to identify Langerhans cell histiocytosis and other immune-related conditions, highlighting its clinical and diagnostic importance.
Características del producto
category
ELISA Kits
immunogen target
T-Cell Surface Glycoprotein CD1a (CD1A)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
R4,T6,CD1,FCB6,HTA1,T-cell surface glycoprotein CD1a,T-cell surface antigen T6/Leu-6,hTa1 thymocyte antigen
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CD1A
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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