Human Somatotropin / Growth Hormone (GH1) Protein

Este producto es parte de GH1 - Growth hormone 1 (Somatotropin)
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208€ (10 µg)

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935106861
info@markelab.com
name
Human Somatotropin / Growth Hormone (GH1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166439
tested applications
WB, SDS-PAGE

Description

Somatotropin / Growth Hormone Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Somatotropin / Growth Hormone (GH1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 25.7 kDa  Observed MW (SDS-PAGE): 23 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Pro28-Phe217
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P01241
Gene ID
2688
OMIM
139250
Alias
GH,GH-N,GHB5,GHN,IGHD1A,IGHD1B,IGHD2,hGH-N,Growth hormone 1,Pituitary growth hormone,HGH
Background
Protein GH1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Growth hormone 1 (Somatotropin) (GH1) is a peptide hormone produced by the anterior pituitary gland that regulates growth, metabolism, and cellular regeneration GH1 plays a central role in stimulating growth during childhood and adolescence by promoting the proliferation and differentiation of chondrocytes in bone tissue, enhancing protein synthesis, and stimulating insulin-like growth factor-1 (IGF-1) production in the liver and peripheral tissues GH1 also regulates carbohydrate and lipid metabolism by enhancing lipolysis, increasing glucose availability, and influencing insulin sensitivity Dysregulation of GH1 production can lead to disorders such as gigantism and acromegaly (overproduction) or growth hormone deficiency, resulting in stunted growth and metabolic imbalances GH1 is also involved in muscle growth, tissue repair, and immune system regulation, highlighting its anabolic and regenerative roles GH1 levels decline with age, contributing to reduced muscle mass and increased fat accumulation, and its therapeutic administration is used to treat growth disorders and promote recovery in catabolic states Its wide-ranging effects on growth, metabolism, and tissue maintenance make GH1 a critical regulator of systemic physiology

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