Human Solute Carrier Family 44 Member 1 (SLC44A1) ELISA Kit

Este producto es parte de SLC44A1 - solute carrier family 44 member 1
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Solute Carrier Family 44 Member 1 (SLC44A1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx383272
tested applications
ELISA

Description

Human Solute Carrier Family 44 Member 1 (SLC44A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Solute Carrier Family 44 Member 1 (SLC44A1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Solute Carrier Family 44 Member 1 (SLC44A1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.094 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8WWI5
Gene ID
23446
OMIM
606105
Alias
Choline transporter-like protein 1,CD92,CTL1,CDW92,CHTL1,CONATOC
Background
Elisa kits for SLC44A1
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

SLC44A1, also known as choline transporter-like protein 1 (CTL1), is a member of the solute carrier family involved in the transport of choline and other organic cations across cell membranes. SLC44A1 plays a crucial role in choline uptake, essential for the synthesis of phosphatidylcholine, a major phospholipid in cellular membranes, and acetylcholine, an important neurotransmitter in the nervous system. SLC44A1 is highly expressed in neuronal cells, kidney cells, and immune cells, reflecting its importance in neurotransmission, cellular membrane integrity, and metabolic regulation. Choline is essential in a variety of biological processes, including methylation reactions, membrane phospholipid synthesis, and acetylcholine production in cholinergic neurons. Deficiency in choline uptake, due to issues with SLC44A1 function, can lead to abnormalities in the nervous system and other health issues. In the brain, SLC44A1 is expressed in regions that are rich in cholinergic neurons, which underscores its importance in supporting neurotransmission. Moreover, SLC44A1 is implicated in mitochondrial function and is involved in phospholipid metabolism pathways, which affect cellular respiration and energy production.

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