Human Lymphocyte Cytosolic Protein 2 (LCP2) Protein
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Description
Human Lymphocyte Cytosolic Protein is a recombinant protein from Human produced in E. coli. Recombinant Human Lymphocyte Cytosolic Protein 2/SH2 Domain-containing Leukocyte Protein of 76 kDa is produced by our E.coli expression system and the target gene encoding Met1-Pro533 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Lymphocyte Cytosolic Protein 2 (LCP2) |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 62.6 kDa Sequence Fragment: Met1-Pro533 Tag: C-terminal 6 His tag Validity: The validity for this protein is 6 months. |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM Tris, 150mM NaCl, 20% glycerol, pH 8.5. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at < -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13094 |
| Background | Protein LCP2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Lymphocyte Cytosolic Protein 2 (LCP2) Antibody
LCP2 Antibody is a Rabbit Polyclonal antibody against LCP2. SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
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Mouse Lymphocyte Cytosolic Protein 2 (LCP2) Protein
Mouse Lymphocyte Cytosolic Protein 2 (LCP2) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
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