Human Signal Regulatory Protein gamma (SIRPg) CLIA Kit
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Description
Human Signal Regulatory Protein gamma (SIRPg) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Signal Regulatory Protein gamma (SIRPg) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.067 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Signal-regulatory protein beta-2,CD172g,SIRPB2,SIRP-B2,bA77C3.1,SIRPgamma,CD172 antigen-like family member B |
| Background | CLIA Kits SIRPG |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Signal Regulatory Protein Gamma (SIRPG) is a member of the signal regulatory protein (SIRP) family, a subset of the immunoglobulin superfamily of cell-surface receptors. SIRPG is encoded by the SIRPG gene located on chromosome 20p13 in humans and is closely related to other family members such as SIRPA (SIRP alpha) and SIRPB (SIRP beta). This receptor plays an important role in immune cell signaling, particularly in immune regulation and cell-cell communication. SIRPG is primarily expressed on cells of the immune system, including T cells and dendritic cells, and plays a significant role in regulating cellular responses involved in immunity. Unlike SIRPA, which interacts with the CD47 ligand on other cells to inhibit macrophage phagocytosis and dendritic cell responses, SIRPG’s role centers on modulating T cell interactions, particularly in the context of immune responses and tissue homeostasis.
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