Human SIGLEC2 (Sialic Acid Binding Ig Like Lectin 2) ELISA Kit

Este producto es parte de CD22 - CD22 molecule
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935106861
info@markelab.com
name
Human SIGLEC2 (Sialic Acid Binding Ig Like Lectin 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH3781
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
15.625-1000pg/ml
Sensitivity
9.375pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P20273
Alias
SIGLEC2,SIGLEC-2,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,T-cell surface antigen Leu-14
Background
Elisa kits for CD22
Status
RUO

CD22, also known as Siglec-2, is a member of the sialic acid-binding immunoglobulin-like lectins (Siglec) family and is predominantly expressed on B cells. It plays a crucial role in modulating B-cell receptor (BCR) signaling and maintaining B-cell tolerance, making it an essential molecule in the regulation of the immune system. CD22 is primarily found on mature B cells, acting both as an inhibitory coreceptor to dampen BCR signaling and as an adhesion molecule involved in cell-cell interactions. CD22 is essential for maintaining the delicate balance between immune activation and tolerance, preventing excessive immune responses that could lead to autoimmune diseases. It is an inhibitory receptor that modulates B-cell activity by recruiting SHP-1, a phosphatase that negatively regulates B-cell signaling pathways. In this capacity, CD22 fine-tunes the immune response to antigens, ensuring that B cells are appropriately activated and preventing autoimmunity.

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Human SIGLEC2 (Sialic Acid Binding Ig Like Lectin 2) ELISA Kit

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