Human Sialomucin Core Protein 24 (CD164) Protein
195€ (10 µg)
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935106861
info@markelab.com
name
Human Sialomucin Core Protein 24 (CD164) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168709
tested applications
WB, SDS-PAGE
Description
Human CD164 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Sialomucin Core Protein 24 (CD164) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 44.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp24-Asp162 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q04900 |
| Alias | Sialomucin core protein 24,DFNA66,MGC-24,MUC-24,MGC-24v,endolyn,Multi-glycosylated core protein 24 |
| Background | Protein CD164 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD164, also known as endolyn or sialomucin core protein 24 (MUC24), is a transmembrane protein involved in cell adhesion and cellular signaling. Expressed predominantly on the surface of hematopoietic progenitor cells and certain epithelial cells, CD164 plays a pivotal role in the regulation of cell migration, proliferation, and differentiation, especially within the hematopoietic system. Located on chromosome 6q21 in humans, the CD164 gene encodes a member of the sialomucin family, which is characterized by its extensive glycosylation and sialic acid residues. CD164 is a crucial molecule in hematopoiesis, as it contributes to the retention of hematopoietic stem cells (HSCs) in their niches and modulates the response of these cells to cytokines and growth factors. Due to its significant roles in cell adhesion and migration, CD164 has been implicated in processes such as immune cell homing, tissue regeneration, and wound healing. Additionally, it plays a role in various diseases, including cancers, where it influences tumor cell migration and metastasis. CD164 is also a biomarker in specific cancer types and a regulator of cellular responses to inflammation.
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