Human Sialomucin Core Protein 24 (CD164) Protein
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935106861
info@markelab.com
Precio
195€ (10 µg)
Protein CD164
proveedor
Abbexareference
abx168709Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human CD164 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
CD164, also known as endolyn or sialomucin core protein 24 (MUC24), is a transmembrane protein involved in cell adhesion and cellular signaling. Expressed predominantly on the surface of hematopoietic progenitor cells and certain epithelial cells, CD164 plays a pivotal role in the regulation of cell migration, proliferation, and differentiation, especially within the hematopoietic system. Located on chromosome 6q21 in humans, the CD164 gene encodes a member of the sialomucin family, which is characterized by its extensive glycosylation and sialic acid residues. CD164 is a crucial molecule in hematopoiesis, as it contributes to the retention of hematopoietic stem cells (HSCs) in their niches and modulates the response of these cells to cytokines and growth factors. Due to its significant roles in cell adhesion and migration, CD164 has been implicated in processes such as immune cell homing, tissue regeneration, and wound healing. Additionally, it plays a role in various diseases, including cancers, where it influences tumor cell migration and metastasis. CD164 is also a biomarker in specific cancer types and a regulator of cellular responses to inflammation.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Sialomucin Core Protein 24 (CD164)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 44.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp24-Asp162 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CD164
dry ice
No
availability
Shipped within 5-7 working days.
alias
Sialomucin core protein 24,DFNA66,MGC-24,MUC-24,MGC-24v,endolyn,Multi-glycosylated core protein 24
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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