Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
662.5€ (96 tests)
Elisa Kits SIGLEC7
proveedor
Abbexareference
abx156745Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
SIGLEC7, also known as p75/AIRM1, is an inhibitory receptor expressed on natural killer (NK) cells and some myeloid cells. It binds preferentially to α2-8-linked disialic acids found on both self and microbial surfaces, helping to suppress inappropriate immune activation. SIGLEC7 transmits inhibitory signals via immunoreceptor tyrosine-based inhibitory motifs (ITIMs), reducing NK cell-mediated cytotoxicity. This protein plays a critical role in maintaining self-tolerance and modulating responses to cancer and viral infections. It is frequently studied for its involvement in tumor immune evasion and as a target for immunotherapy.
Características del producto
category
ELISA Kits
immunogen target
Sialic Acid Binding Ig Like Lectin 7 (SIGLEC7)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
p75,QA79,AIRM1,CD328,AIRM-1,CDw328,D-siglec,SIGLEC-7,SIGLECP2,SIGLEC19P,p75/AIRM1,Adhesion inhibitory receptor molecule 1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SIGLEC7
dry ice
No
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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