Human Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) ELISA Kit

Este producto es parte de SIGLEC - sialic acid binding Ig like lectin
Human Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits SIGLEC15

proveedor

Abbexa

reference

abx545883

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

SIGLEC15 is predominantly expressed on macrophages, dendritic cells, and osteoclasts. Unlike other Siglecs, SIGLEC15 shows specificity for modified sialic acids and is crucial for osteoclast development and bone resorption. It interacts with ligands on T cells to regulate immune responses, making it a potential target for cancer immunotherapy as it suppresses anti-tumor immunity. SIGLEC15 is highly expressed in the tumor microenvironment and has been associated with poor prognosis in certain cancers. Its roles extend to tissue remodeling and maintaining immune homeostasis in non-inflammatory conditions.

Características del producto

category

ELISA Kits


immunogen target

Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.06 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

CD33L3,HsT1361,SIGLEC-15,CD33 antigen-like 3


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

SIGLEC15


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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reactivity

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reactivity

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reference

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Tested Applications

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reactivity

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status

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clonality

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