Human Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) ELISA Kit
![Human Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) ELISA Kit](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fcatalog%2FGraphs%2F29%2Fabx545883%2Fabx545883_Human_Sialic_Acid_Binding_Ig_Like_Lectin_15_SIGLEC15_ELISA_Kit_graph-250x250.png&w=3840&q=75)
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits SIGLEC15
proveedor
Abbexareference
abx545883Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
SIGLEC15 is predominantly expressed on macrophages, dendritic cells, and osteoclasts. Unlike other Siglecs, SIGLEC15 shows specificity for modified sialic acids and is crucial for osteoclast development and bone resorption. It interacts with ligands on T cells to regulate immune responses, making it a potential target for cancer immunotherapy as it suppresses anti-tumor immunity. SIGLEC15 is highly expressed in the tumor microenvironment and has been associated with poor prognosis in certain cancers. Its roles extend to tissue remodeling and maintaining immune homeostasis in non-inflammatory conditions.
Características del producto
category
ELISA Kits
immunogen target
Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
CD33L3,HsT1361,SIGLEC-15,CD33 antigen-like 3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SIGLEC15
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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