Human SH2 Domain Containing 3A (SH2D3A) ELISA Kit

Este producto es parte de SH2D - SH2 domain containing
Human SH2 Domain Containing 3A (SH2D3A) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for SH2D3A

proveedor

Abbexa

reference

abx383169

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human SH2 Domain Containing 3A (SH2D3A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SH2D3A concentrations in serum, plasma and other biological fluids.


Background

SH2D3A, also known as NSP1 (novel SH2-containing protein 1), is an adaptor protein containing an SH2 domain and a proline-rich region that mediates interactions with signaling molecules in receptor tyrosine kinase pathways. It is involved in regulating actin cytoskeletal remodeling, cell adhesion, and migration by linking signaling proteins like Crk-associated substrates (CAS) to downstream effectors. SH2D3A plays a key role in integrin-mediated signaling and growth factor receptor activation, particularly during cell motility and adhesion processes. It is highly expressed in tissues undergoing dynamic changes, such as embryonic development and wound healing. Dysregulation of SH2D3A has been linked to cancer progression, where it promotes metastasis and invasion through actin cytoskeletal reorganization and integrin activation. Knockout studies reveal defects in cell migration, adhesion, and spreading, underscoring its importance in cellular movement and signal transduction.

Características del producto

category

ELISA Kits


immunogen target

SH2 Domain Containing 3A (SH2D3A)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

SH2D3A, NSP1, SH2 domain containing 3A


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

SH2D3A


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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