Human SH2 Domain Containing 3A (SH2D3A) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human SH2 Domain Containing 3A (SH2D3A) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx383169
tested applications
ELISA
Description
Human SH2 Domain Containing 3A (SH2D3A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SH2D3A concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | SH2 Domain Containing 3A (SH2D3A) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9BRG2 |
| Gene ID | 10045 |
| OMIM | 604721 |
| Alias | SH2D3A, NSP1, SH2 domain containing 3A |
| Background | Elisa kits for SH2D3A |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
SH2D3A, also known as NSP1 (novel SH2-containing protein 1), is an adaptor protein containing an SH2 domain and a proline-rich region that mediates interactions with signaling molecules in receptor tyrosine kinase pathways. It is involved in regulating actin cytoskeletal remodeling, cell adhesion, and migration by linking signaling proteins like Crk-associated substrates (CAS) to downstream effectors. SH2D3A plays a key role in integrin-mediated signaling and growth factor receptor activation, particularly during cell motility and adhesion processes. It is highly expressed in tissues undergoing dynamic changes, such as embryonic development and wound healing. Dysregulation of SH2D3A has been linked to cancer progression, where it promotes metastasis and invasion through actin cytoskeletal reorganization and integrin activation. Knockout studies reveal defects in cell migration, adhesion, and spreading, underscoring its importance in cellular movement and signal transduction.
Related Products
Sh2 Domain Containing 3A (SH2D3A) Antibody
Sh2 Domain Containing 3A Antibody is a Rabbit Polyclonal antibody against Sh2 Domain Containing 3A.
Ver Producto
SH2 Domain Containing 3A (SH2D3A) Antibody
SH2D3A Antibody is a Rabbit Polyclonal against SH2D3A.
Ver Producto