Human Serum Amyloid P Component (SAP) is a recombinant Human protein produced in E. coli using Prokaryotic expression.
SAP, also known as PTX2, belongs to the pentraxin family. Has the ability to bind ligands in a calcium-dependent manner and its unique flattened β-jellyroll structure, which bears resemblance to the structure found in legume lectins. APCS is its human gene.SAP is exclusively produced in the liver, and as a standard plasma protein, it is naturally present in all individuals. While it enters the brain in only minuscule quantities under normal conditions, it is consistently found in the cerebrospinal fluid. AP possesses the capacity to bind to both amyloid plaques and tau tangles, effectively stabilizing and stabilise aggregates by preventing proteolytic cleavage and hence inhibiting fibril removal. It ia also known as: APCS, PTX2, SAP, AP, Amyloid P Component
Proteins and Peptides
Human
E. coli
Serum Amyloid P Component (SAP)
E. coli
Unconjugated
Lyophilized
WB, SDS-PAGE
10 µg
50 µg
100 µg
200 µg
1 mg
Recombinant
> 95%
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
SAP
No
Shipped within 5-7 working days.
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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