Human Serpin Family E Member 1 (SERPINE1) Enzyme
Pida mas información
935106861
info@markelab.com
Precio
234€ (5 µg)
Protein SERPINE1
proveedor
Abbexareference
abx073514Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Plasminogen Activator Inhibitor-1 is a recombinant enzyme.
Background
SERPINE1, also known as Plasminogen Activator Inhibitor-1 (PAI1), is a serine protease inhibitor that plays a key role in the regulation of fibrinolysis, the process that breaks down blood clots. It belongs to the serpin superfamily, which is a group of proteins involved in the inhibition of proteases. Specifically, SERPINE1 inhibits tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), both of which are enzymes responsible for converting plasminogen into plasmin, a protease that degrades fibrin, the main component of blood clots. The regulation of PAI-1 levels is crucial for maintaining the balance between clot formation and breakdown in the body. Abnormally high levels of PAI-1 are associated with thrombotic conditions, whereas deficiencies can lead to excessive bleeding.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Serpin Family E Member 1 (SERPINE1)
host
E. coli
form
Liquid
tested applications
SDS-PAGE
size 1
5 µg
size 2
25 µg
size 3
1 mg
expression
Recombinant
purity
> 95% (SDS-PAGE)
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
storage
Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
or code
SERPINE1
dry ice
No
availability
Shipped within 5-10 working days.
alias
PAI,PAI1,PAI-1,PLANH1,Plasminogen activator inhibitor 1,Endothelial plasminogen activator inhibitor,Serpin E1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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