Human Semaphorin 7A (SEMA7A) Protein

Este producto es parte de SEMA7A - semaphorin 7A
Product Graph
208€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Semaphorin 7A (SEMA7A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069035
tested applications
WB, SDS-PAGE

Description

Recombinant Semaphorin 7A (SEMA7A) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Semaphorin 7A (SEMA7A)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 34.0 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Tyr242-Arg507

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O75326
Alias
JohnMiltonHagen blood group,JMH,CD108,SEMAL,CDw108,PFIC11,SEMAK1,H-Sema-L,H-SEMA-K1,JMH blood group antigen,Semaphorin-K1,Semaphorin-L
Background
Protein SEMA7A
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Semaphorin 7A (SEMA7A) is a membrane-associated protein that belongs to the semaphorin family, a group of proteins widely recognized for their roles in axon guidance, immune response, and cellular signaling. Semaphorins, initially identified as axon-guidance molecules, are now understood to function across a variety of biological systems, impacting cell-cell interactions, cell migration, and immune cell regulation. SEMA7A, also referred to as CD108, is distinct from other semaphorins due to its glycophosphatidylinositol (GPI) anchorage, allowing it to localize on the cell surface and interact with various receptors. SEMA7A is broadly expressed in a range of tissues, including the nervous system, immune cells, skin, and certain cancer types. It is known to participate in axonal guidance, immune regulation, bone development, and pathological conditions, such as tumorigenesis and fibrotic diseases. One of its key functions is promoting axonal outgrowth and guiding neural connections, mediated through its interactions with integrins and other receptors. Furthermore, SEMA7A is actively involved in inflammatory and immune responses, modulating immune cell migration, adhesion, and activation. This diversity in function makes SEMA7A a molecule of interest in fields ranging from neurobiology to immunology and oncology.

Related Products

EH3766

Human SEMA7A (Semaphorin 7A) ELISA Kit

Ver Producto
abx126529

Semaphorin 7A (SEMA7A) Antibody

SEMA7A Antibody is a Rabbit Polyclonal against SEMA7A.

Ver Producto
abx196260

Human Semaphorin 7A (SEMA7A) CLIA Kit

Human Semaphorin 7A (SEMA7A) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Semaphorin 7A (SEMA7A).

Ver Producto